The Futurama Season 5 Premiere on November the 10th will be the episode "Crimes of the Hot" according to TVGuide. The time seems to be 7pm/6c again, which will open it up for ample football pre-emption and "already in progress" showing where applicable (Washington, Cincinnati, Houston, etc).
Now to the episode:
FOX seems to have chosen to take a "mid production-season 4 episode" (4ACV08) as the premiere because it features a guest star: Al Gore - voiced by himself.
It should be fun to see how the Futurama staff managed to integrate both Al Gore and Kyoto into an episode when his political opponent tried to rip the protocoll apart. It's a bit of a shame though that we'll be in the 5th season and still didn't see all episodes produced for season 3.
As Earth is unable to counter its rising temperature through the usual method (the dropping of a giant ice cube into the ocean), Gore leads an emergency conference in Kyoto, Japan, where Professor Farnsworth claims responsibility for the crisis. It seems love detoured him from observing proper emission standards on his prototype robot, and that could necessitate the destruction of all its "descendants." That includes Bender, who resigns himself to having a farewell blowout before being blown up.