Since 1999, Futurama has had a spot in the San Diego Comic-Con with panel discussions, episode viewings, and autograph signings. But this year there'll be a little less of the Future at Comic-Con. Futurama doesn't have a planned panel discussion, and Matt Groening might not even be attending the four-day event come July 22nd. The information is pretty sketchy at the moment, but there seems to be a Simpsons panel discussion happening at Comic-Con. This information isn't official, seeing as the official CC website doesn't give much information. But sources from the Simpsons production have said there will be a panel for the show.
If you're going to the Con whether or not Futurama or Matt G.'s going to be there, check out the Bongo Comics booth. Futurama writers/artists might be hanging out there signing whatever you have in your backpack. The Bongo booth normally has very rare Futurama and Bongo-related items for auction or sale, so be sure to take some extra cash.
Turns out Billy West, our beloved voice of Fry, Zoidberg, and Zapp, along with others, will infact be attending Comic-Con! He'll be sharing booth space with Steve Troop's MELONPOOL (Booth 1420) and will also be appearing on Mark Evanier's Cartoon Voice Actors panel (Saturday, July 24, 1:30 PM - 3:00 PM / Room 6AB.)
Thanks to Ken and TVsEgon for the info.